Journal: International Journal of Molecular Sciences
Article Title: Integration of Multiomics Data Reveals Selection Characteristics of ITGB1 That Are Associated with Size Differentiation in Pigs
doi: 10.3390/ijms26041569
Figure Lengend Snippet: Volcano map and selective signal analysis of DEGs and Venn map of DEGs between EM pigs and HB pigs at the same stage. ( a ) Each volcano plot displays gene expression changes at different time points (1 day, 30 days, 60 days, 90 days, and 120 days). The x -axis represents the log2 fold change, and the y -axis shows the −Log10 p -value. Genes are color-coded as follows: gray (nonsignificant), blue (significant log2 fold change only), green (significant p -value only), and red (both significant). The vertical dashed lines indicate a 2-fold change threshold, and the horizontal dashed line represents the significance threshold at p < 0.05. The total number of variables analyzed is 9338. ( b ) Venn diagram displaying the overlap of genes identified by XP-EHH, the F ST /θ π ratio, and DESeq2 differential expression analysis. A total of 41 genes were identified by all three methods, as shown in the central overlapping region.
Article Snippet: The DESeq2 tool (v1.46) on the Meiji BioCloud platform ( https://cloud.majorbio.com/ , accessed on 25 April 2024) [ ] was employed for this analysis, applying screening criteria of |log2Fold Change| > 1 and a Q value < 0.05 to effectively control the false-positive rate.
Techniques: Gene Expression, Quantitative Proteomics